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IgA as a potential candidate for enteric monoclonal antibody therapeutics with improved gastrointestinal stability

Mucosal surfaces of the gastrointestinal tract play an important role in immune homeostasis and defense and may be compromised by enteric disorders or infection. Therapeutic intervention using monoclonal antibody (mAb) offers the potential for treatment with minimal off-target effects as well as the...

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Detalles Bibliográficos
Publicado en:Vaccine
Main Authors: Wallace, Aaron L., Schneider, Matthew I., Toomey, Jacqueline R., Schneider, Ryan M., Klempner, Mark S., Wang, Yang, Cavacini, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604562/
https://ncbi.nlm.nih.gov/pubmed/33041102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.09.070
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