IgA as a potential candidate for enteric monoclonal antibody therapeutics with improved gastrointestinal stability

Mucosal surfaces of the gastrointestinal tract play an important role in immune homeostasis and defense and may be compromised by enteric disorders or infection. Therapeutic intervention using monoclonal antibody (mAb) offers the potential for treatment with minimal off-target effects as well as the...

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Foilsithe in:Vaccine
Main Authors: Wallace, Aaron L., Schneider, Matthew I., Toomey, Jacqueline R., Schneider, Ryan M., Klempner, Mark S., Wang, Yang, Cavacini, Lisa A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier Science 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604562/
https://ncbi.nlm.nih.gov/pubmed/33041102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.09.070
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