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Rhodopsin-mediated light-off-induced protein kinase A activation in mouse rod photoreceptor cells

Light-induced extrasynaptic dopamine release in the retina reduces adenosine 3′,5′-cyclic monophosphate (cAMP) in rod photoreceptor cells, which is thought to mediate light-dependent desensitization. However, the fine time course of the cAMP dynamics in rods remains elusive due to technical difficul...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sato, Shinya, Yamashita, Takahiro, Matsuda, Michiyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604457/
https://ncbi.nlm.nih.gov/pubmed/33046651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009164117
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