Ethyl Acetate Extract of Selaginella doederleinii Hieron Induces Cell Autophagic Death and Apoptosis in Colorectal Cancer via PI3K-Akt-mTOR and AMPKα-Signaling Pathways

Colorectal cancer is one type of cancer with high incidence rate and high mortality worldwide. Thus, developing new chemotherapeutic drugs is important. The Selaginella doederleinii Hieron ethyl acetate (SDEA) extract showed good anti-colon cancer effect in vitro and in vivo, but its mechanism is un...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Shaoguang, Wang, Xuewen, Wang, Gang, Shi, Peiying, Lin, Shilan, Xu, Dafen, Chen, Bing, Liu, Ailin, Huang, Liying, Lin, Xinhua, Yao, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604386/
https://ncbi.nlm.nih.gov/pubmed/33192508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.565090
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