Ethyl Acetate Extract of Selaginella doederleinii Hieron Induces Cell Autophagic Death and Apoptosis in Colorectal Cancer via PI3K-Akt-mTOR and AMPKα-Signaling Pathways

Colorectal cancer is one type of cancer with high incidence rate and high mortality worldwide. Thus, developing new chemotherapeutic drugs is important. The Selaginella doederleinii Hieron ethyl acetate (SDEA) extract showed good anti-colon cancer effect in vitro and in vivo, but its mechanism is un...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Li, Shaoguang, Wang, Xuewen, Wang, Gang, Shi, Peiying, Lin, Shilan, Xu, Dafen, Chen, Bing, Liu, Ailin, Huang, Liying, Lin, Xinhua, Yao, Hong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604386/
https://ncbi.nlm.nih.gov/pubmed/33192508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.565090
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