The Recombinant Protein Based on Trypanosoma cruzi P21 Interacts With CXCR4 Receptor and Abrogates the Invasive Phenotype of Human Breast Cancer Cells

Trypanosoma cruzi P21 is a protein secreted by the parasite that plays biological roles directly involved in the progression of Chagas disease. The recombinant protein (rP21) demonstrates biological properties, such as binding to CXCR4 receptors in macrophages, chemotactic activity of immune cells,...

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Publicado en:Front Cell Dev Biol
Main Authors: Borges, Bruna Cristina, Uehara, Isadora Akemi, dos Santos, Marlus Alves, Martins, Flávia Alves, de Souza, Fernanda Carvalho, Junior, Álvaro Ferreira, da Luz, Felipe Andrés Cordero, da Costa, Mylla Spirandelli, Notário, Ana Flávia Oliveira, Lopes, Daiana Silva, Teixeira, Samuel Cota, Teixeira, Thaise Lara, de Castilhos, Patrícia, da Silva, Claudio Vieira, Silva, Marcelo José Barbosa
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604327/
https://ncbi.nlm.nih.gov/pubmed/33195200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.569729
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