Notoginseng Leaf Triterpenes Ameliorates OGD/R-Induced Neuronal Injury via SIRT1/2/3-Foxo3a-MnSOD/PGC-1α Signaling Pathways Mediated by the NAMPT-NAD Pathway

BACKGROUND: Cerebral ischemic stroke (CIS) is a common cerebrovascular disease whose main risks include necrosis, apoptosis, and cerebral infarction. But few therapeutic advances and prominent drugs seem to be of value for ischemic stroke in the clinic yet. In the previous study, notoginseng leaf tr...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Xie, Weijie, Zhu, Ting, Zhou, Ping, Xu, Huibo, Meng, Xiangbao, Ding, Tao, Nan, Fengwei, Sun, Guibo, Sun, Xiaobo
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603631/
https://ncbi.nlm.nih.gov/pubmed/33149812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7308386
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