Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death

Mitochondrial oxidative stress and dysfunction play an important role of atrial remodeling and atrial fibrillation (AF) in diabetes mellitus. Endoplasmic reticulum (ER) stress has been linked to both physiological and pathological states including diabetes. The aim of this project is to explore the...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Yuan, Ming, Gong, Mengqi, Zhang, Zhiwei, Meng, Lei, Tse, Gary, Zhao, Yungang, Bao, Qiankun, Zhang, Yue, Yuan, Meng, Liu, Xing, Li, Guangping, Liu, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603626/
https://ncbi.nlm.nih.gov/pubmed/33149811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6569728
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