Pharmacogenetic Association between XRCC1 Polymorphisms and Response to Platinum-Based Chemotherapy in Asian Patients with NSCLC: A Meta-Analysis

BACKGROUND: Platinum-based chemotherapy plays an antitumor role by damaging DNA. X-ray repair crosscomplementing protein 1 (XRCC1) participates in DNA repair and thus affects the sensitivity to platinum drugs. Two polymorphisms of XRCC1, rs25487 (Arg399Gln) and rs1799782 (Arg194Trp), have been widel...

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Publicat a:Biomed Res Int
Autors principals: Zhang, Ningning, Ouyang, Yushu, Chang, Jianlan, Liu, Ping, Tian, Xiangyang, Yu, Junyan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603545/
https://ncbi.nlm.nih.gov/pubmed/33150172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3520764
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