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Nonalcoholic Fatty Liver Disease Impairs the Liver–Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

Nonalcoholic fatty liver disease (NAFLD) is associated with impaired hepatic actions of glucagon and insulin. Glucagon and amino acids are linked in an endocrine feedback circuit, the liver–alpha cell axis, that may be disrupted by NAFLD. We investigated how NAFLD severity affects glucagon and insul...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Pedersen, Julie Steen, Rygg, Marte Opseth, Kristiansen, Viggo Bjerregaard, Olsen, Beth Hærstedt, Serizawa, Reza Rafiolsadat, Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming, Wewer Albrechtsen, Nicolai Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603528/
https://ncbi.nlm.nih.gov/pubmed/33163832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1562
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