Crbn modulates calcium influx by regulating Orai1 during efferocytosis

Calcium flux regulating intracellular calcium levels is essential and modulated for efficient efferocytosis. However, the molecular mechanism by which calcium flux is modulated during efferocytosis remains elusive. Here, we report that Orai1, a Crbn substrate, is upregulated via its attenuated inter...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Moon, Hyunji, Min, Chanhyuk, Kim, Gayoung, Kim, Deokhwan, Kim, Kwanhyeong, Lee, Sang-Ah, Moon, Byeongjin, Yang, Susumin, Lee, Juyeon, Yang, Seung-Joo, Cho, Steve K., Lee, Gwangrog, Lee, Chang Sup, Park, Chul-Seung, Park, Daeho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603501/
https://ncbi.nlm.nih.gov/pubmed/33127885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19272-0
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