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Common and Rare Variants in Genes Associated with von Willebrand Factor Level Variation: No Accumulation of Rare Variants in Swedish von Willebrand Disease Patients

Genome-wide association studies (GWASs) have identified genes that affect plasma von Willebrand factor (VWF) levels. ABO showed a strong effect, whereas smaller effects were seen for VWF , STXBP5 , STAB2 , SCARA5 , STX2 , TC2N , and CLEC4M . This study screened comprehensively for both common and ra...

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Publicado en:TH Open
Main Authors: Manderstedt, Eric, Lind-Halldén, Christina, Lethagen, Stefan, Halldén, Christer
Formato: Artigo
Idioma:Inglês
Publicado: Georg Thieme Verlag KG 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603419/
https://ncbi.nlm.nih.gov/pubmed/33145474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1718885
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