In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach

Although increasing used in the preclinical testing of new anti-fibrotic drugs, a thorough validation of micro-computed tomography (CT) in pulmonary fibrosis models has not been performed. Moreover, no attempts have been made so far to define density thresholds to discriminate between aeration level...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mecozzi, Laura, Mambrini, Martina, Ruscitti, Francesca, Ferrini, Erica, Ciccimarra, Roberta, Ravanetti, Francesca, Sverzellati, Nicola, Silva, Mario, Ruffini, Livia, Belenkov, Sasha, Civelli, Maurizio, Villetti, Gino, Stellari, Fabio Franco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603396/
https://ncbi.nlm.nih.gov/pubmed/33127949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71293-3
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