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Comparison of next-generation sequencing (NGS) and next-generation flow (NGF) for minimal residual disease (MRD) assessment in multiple myeloma

Detecting persistent minimal residual disease (MRD) allows the identification of patients with an increased risk of relapse and death. In this study, we have evaluated MRD 3 months after transplantation in 106 myeloma patients using a commercial next-generation sequencing (NGS) strategy (LymphoTrack...

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Veröffentlicht in:Blood Cancer J
Hauptverfasser: Medina, Alejandro, Puig, Noemi, Flores-Montero, Juan, Jimenez, Cristina, Sarasquete, M.-Eugenia, Garcia-Alvarez, María, Prieto-Conde, Isabel, Chillon, Carmen, Alcoceba, Miguel, Gutierrez, Norma C., Oriol, Albert, Rosinol, Laura, Bladè, Joan, Gironella, Mercedes, Hernandez, Miguel T., Gonzalez-Calle, Veronica, Cedena, Maria-Teresa, Paiva, Bruno, San-Miguel, Jesus F., Lahuerta, Juan-Jose, Mateos, Maria-Victoria, Martinez-Lopez, Joaquin, Orfao, Alberto, Gonzalez, Marcos, Garcia-Sanz, Ramon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603393/
https://ncbi.nlm.nih.gov/pubmed/33127891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-00377-0
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