Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer

Human epidermal growth factor receptor 2 (HER2) protein overexpression or gene amplification is an important predictive biomarker for identifying patients with breast cancer, who may benefit from HER2-targeted therapy. However, little is known about the molecular landscape and efficacy of HER2-targe...

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Udgivet i:NPJ Breast Cancer
Main Authors: Yi, Zongbi, Rong, Guohua, Guan, Yanfang, Li, Jin, Chang, Lianpeng, Li, Hui, Liu, Binliang, Wang, Wenna, Guan, Xiuwen, Ouyang, Quchang, Li, Lixi, Zhai, Jingtong, Li, Chunxiao, Li, Lifeng, Xia, Xuefeng, Yang, Ling, Qian, Haili, Yi, Xin, Xu, Binghe, Ma, Fei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603305/
https://ncbi.nlm.nih.gov/pubmed/33145402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-020-00201-9
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