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Methylation of the PKD1 Promoter Inversely Correlates with its Expression in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD), a multisystem disorder, is the most prevalent type of hereditary kidney disease. Here, we aimed to evaluate methylation of the PKD1 gene (PKD1) promoter and its correlation with PKD1 expression in peripheral blood. METHODS: In this ca...

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Bibliografski detalji
Izdano u:Rep Biochem Mol Biol
Glavni autori: Hajirezaei, Fatemeh, Ghaderian, Sayyed Mohammad Hossein, Hasanzad, Mandana, Nafar, Mohsen, Ghadiani, Mohammad Hasan, Biglari, Sajjad, Sohrabifar, Nasim, Jafari, Hossein
Format: Artigo
Jezik:Inglês
Izdano: Varastegan Institute for Medical Sciences 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603252/
https://ncbi.nlm.nih.gov/pubmed/33178869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/rbmb.9.2.193
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