Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells

The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) is considered as the master regulator of antioxidant and cytoprotective gene expressions. Moreover, it plays a pivotal role in cancer progression. Nrf2 mediates the adaptive response which contributes to the resistance to ch...

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Bibliografske podrobnosti
izdano v:Antioxidants (Basel)
Main Authors: Ambrosio, Leanne, Argenziano, Monica, Cucci, Marie Angèle, Grattarola, Margherita, de Graaf, Inge A.M., Dianzani, Chiara, Barrera, Giuseppina, Sánchez Nieves, Javier, Gomez, Rafael, Cavalli, Roberta, Pizzimenti, Stefania
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602517/
https://ncbi.nlm.nih.gov/pubmed/33066634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9100993
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