Screening for sickle cell disease in newborns: a systematic review

BACKGROUND: Sickle cell disease (SCD) is an inherited autosomal recessive disorder caused by the replacement of normal haemoglobin (HbA) by mutant Hb (sickle Hb, HbS). The sickle-shaped red blood cells lead to haemolysis and vaso-occlusion. Especially in the first years of life, patients with SCD ar...

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Detalhes bibliográficos
Publicado no:Syst Rev
Main Authors: Runkel, Britta, Klüppelholz, Birgit, Rummer, Anne, Sieben, Wiebke, Lampert, Ulrike, Bollig, Claudia, Markes, Martina, Paschen, Ulrike, Angelescu, Konstanze
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602310/
https://ncbi.nlm.nih.gov/pubmed/33126922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-020-01504-5
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