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Synthesis of 4,4′-(4-Formyl-1H-pyrazole-1,3-diyl)dibenzoic Acid Derivatives as Narrow Spectrum Antibiotics for the Potential Treatment of Acinetobacter Baumannii Infections

Acinetobacter baumannii has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors of A. baumannii strains with a minimum inhibitory...

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Библиографические подробности
Опубликовано в: :Antibiotics (Basel)
Главные авторы: Delancey, Evan, Allison, Devin, KC, Hansa Raj, Gilmore, David F., Fite, Todd, Basnakian, Alexei G., Alam, Mohammad A.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601628/
https://ncbi.nlm.nih.gov/pubmed/32998384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9100650
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