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Fumonisin B(1) Epigenetically Regulates PTEN Expression and Modulates DNA Damage Checkpoint Regulation in HepG2 Liver Cells

Fumonisin B(1) (FB(1)), a Fusarium-produced mycotoxin, is found in various foods and feeds. It is a well-known liver carcinogen in experimental animals; however, its role in genotoxicity is controversial. The current study investigated FB(1)-triggered changes in the epigenetic regulation of PTEN and...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Arumugam, Thilona, Ghazi, Terisha, Chuturgoon, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601513/
https://ncbi.nlm.nih.gov/pubmed/33007920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12100625
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