Widespread Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates

Venomous snakes are important subjects of study in evolution, ecology, and biomedicine. Many venomous snakes have alpha-neurotoxins (α-neurotoxins) in their venom. These toxins bind the alpha-1 nicotinic acetylcholine receptor (nAChR) at the neuromuscular junction, causing paralysis and asphyxia. Se...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Khan, Muzaffar A., Dashevsky, Daniel, Kerkkamp, Harald, Kordiš, Dušan, de Bakker, Merijn A. G., Wouters, Roel, van Thiel, Jory, op den Brouw, Bianca, Vonk, Freek J., Kini, R. Manjunatha, Nazir, Jawad, Fry, Bryan G., Richardson, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601176/
https://ncbi.nlm.nih.gov/pubmed/33023159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12100638
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