Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway

Increased circulatory and adipose tissue expression of macrophage inflammatory protein (MIP)-1α (CC motif chemokine ligand-3/CCL3) and its association with inflammation in the state of obesity is well documented. Since obesity is associated with increases in both stearic acid and tumor necrosis fact...

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Veröffentlicht in:Biomedicines
Hauptverfasser: Kochumon, Shihab, Arefanian, Hossein, Azim, Rafaat, Shenouda, Steve, Jacob, Texy, Abu Khalaf, Nermeen, Al-Rashed, Fatema, Hasan, Amal, Sindhu, Sardar, Al-Mulla, Fahd, Ahmad, Rasheed
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600458/
https://ncbi.nlm.nih.gov/pubmed/33050324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100403
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