Moderate SIRT1 overexpression protects against brown adipose tissue inflammation

OBJECTIVE: Metainflammation is a chronic low-grade inflammatory state induced by obesity and associated comorbidities, including peripheral insulin resistance. Brown adipose tissue (BAT), a therapeutic target against obesity, is an insulin target tissue sensitive to inflammation. Therefore, it is ne...

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Bibliografische gegevens
Gepubliceerd in:Mol Metab
Hoofdauteurs: Escalona-Garrido, Carmen, Vázquez, Patricia, Mera, Paula, Zagmutt, Sebastián, García-Casarrubios, Ester, Montero-Pedrazuela, Ana, Rey-Stolle, Fernanda, Guadaño-Ferraz, Ana, Rupérez, Francisco J., Serra, Dolors, Herrero, Laura, Obregon, Maria Jesus, Valverde, Ángela M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600394/
https://ncbi.nlm.nih.gov/pubmed/33049408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101097
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