Quasi-Irreversible Inhibition of CYP2D6 by Berberine

In our previous study, Hwang-Ryun-Hae-Dok-Tang, which contains berberine (BBR) as a main active ingredient, inhibited cytochrome P450 (CYP) 2D6 in a quasi-irreversible manner. However, no information is available on the detailed mechanism of BBR-induced CYP2D6 inhibition. Thus, the present study aim...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Kim, Ha Gyeong, Lee, Han Sol, Jeon, Jang Su, Choi, Young Jae, Choi, Yeon Jung, Yoo, So-Yeol, Kim, Eun-yeong, Lee, Kiho, Park, InWha, Na, MinKyun, Park, Han-Jin, Cho, Seung-Woo, Kim, Jong-Hoon, Lee, Jae-Young, Kim, Sang Kyum
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600264/
https://ncbi.nlm.nih.gov/pubmed/32987920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12100916
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