α-Bisabolol, a Dietary Bioactive Phytochemical Attenuates Dopaminergic Neurodegeneration through Modulation of Oxidative Stress, Neuroinflammation and Apoptosis in Rotenone-Induced Rat Model of Parkinson’s Disease

Rotenone (ROT), a plant-derived pesticide is a well-known environmental neurotoxin associated with causation of Parkinson’s disease (PD). ROT impairs mitochondrial dysfunction being mitochondrial complex-I (MC-1) inhibitor and perturbs antioxidant-oxidant balance that contributes to the onset and de...

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Udgivet i:Biomolecules
Main Authors: Javed, Hayate, Meeran, M. F. Nagoor, Azimullah, Sheikh, Bader Eddin, Lujain, Dwivedi, Vivek Dhar, Jha, Niraj Kumar, Ojha, Shreesh
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599960/
https://ncbi.nlm.nih.gov/pubmed/33049992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10101421
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