Long-Term Helicobacter pylori Infection Switches Gastric Epithelium Reprogramming towards Cancer Stem Cell-Related Differentiation Program in Hp-Activated Gastric Fibroblast-TGFβ Dependent Manner

Helicobacter pylori (Hp)-induced inflammatory reaction leads to a persistent disturbance of gastric mucosa and chronic gastritis evidenced by deregulation of tissue self-renewal and local fibrosis with the crucial role of epithelial–mesenchymal transition (EMT) in this process. As we reported before...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Krzysiek-Maczka, Gracjana, Targosz, Aneta, Szczyrk, Urszula, Wrobel, Tomasz, Strzalka, Malgorzata, Brzozowski, Tomasz, Czyz, Jaroslaw, Ptak-Belowska, Agata
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599721/
https://ncbi.nlm.nih.gov/pubmed/33023180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8101519
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