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Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways

SIMPLE SUMMARY: Investigation into effective targets of drug resistance is important for identifying novel strategies in cancer therapy. The study aimed to determine the functional role of paclitaxel (PTX) resistance on MCF-7 cell survival related to PI3K/Akt and MAPK pathways. Therefore, we generat...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Ozfiliz Kilbas, Pelin, Sonmez, Ozlem, Uysal-Onganer, Pinar, Coker Gurkan, Ajda, Obakan Yerlikaya, Pinar, Arisan, Elif Damla
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599514/
https://ncbi.nlm.nih.gov/pubmed/33019717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9100320
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