High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection

SIMPLE SUMMARY: The G2M checkpoint pathway is a critical step in the cell cycle, which is one of the hallmarks in cancer. We investigated clinical relevance of the G2M pathway in pancreatic cancer, using gene set variation analysis (GSVA) with Hallmark G2M checkpoint gene set. High G2M score tumors...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Oshi, Masanori, Newman, Stephanie, Tokumaru, Yoshihisa, Yan, Li, Matsuyama, Ryusei, Endo, Itaru, Katz, Matthew H. G., Takabe, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599494/
https://ncbi.nlm.nih.gov/pubmed/33036243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102871
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