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Association of a dysbiotic oral microbiota with the development of focal lymphocytic sialadenitis in IκB-ζ-deficient mice

Mice lacking IκB-ζ, a protein encoded by the Nfkbiz gene, spontaneously develop a Sjögren’s syndrome-like disease involving the lachrymal glands, but no salivary gland symptoms have been reported. We found that Nfkbiz(−/−) female mice presented a significantly reduced salivary flow rate, focal lymph...

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Biofilms Microbiomes
Hauptverfasser: Lee, Junho, Alam, Jehan, Choi, Eunji, Ko, Yeon Kyeong, Lee, Ahreum, Choi, Youngnim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599236/
https://ncbi.nlm.nih.gov/pubmed/33127905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41522-020-00158-4
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