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Carboplatin dose capping affects pCR rate in HER2-positive breast cancer patients treated with neoadjuvant Docetaxel, Carboplatin, Trastuzumab, Pertuzumab (TCHP)

PURPOSE: Estimated glomerular filtration rate (eGFR) is commonly used to calculate carboplatin doses and capping the eGFR may be used to reduce the risk of excessive dosing and toxicity. We sought to retrospectively examine the impact of our carboplatin guidelines on pathological complete response r...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Howell, Sacha J., Coe, Faye, Wang, Xin, Horsley, Laura, Ekholm, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599187/
https://ncbi.nlm.nih.gov/pubmed/32860550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05868-z
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