Nanoparticles in 472 Human Cerebrospinal Fluid: Changes in Extracellular Vesicle Concentration and miR-21 Expression as a Biomarker for Leptomeningeal Metastasis

SIMPLE SUMMARY: Leptomeningeal metastasis (LM) is a terminal stage cancer manifestation to whole neuraxis via cerebrospinal fluid (CSF). Up to now, LM has no solid biomarkers for disease progression or treatment response. Extracellular vesicles (EVs) in biofluids have been recently studied to evalua...

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Pubblicato in:Cancers (Basel)
Autori principali: Lee, Kyue-Yim, Im, Ji Hye, Lin, Weiwei, Gwak, Ho-Shin, Kim, Jong Heon, Yoo, Byong Chul, Kim, Tae Hoon, Park, Jong Bae, Park, Hyeon Jin, Kim, Ho-Jin, Kwon, Ji-Woong, Shin, Sang Hoon, Yoo, Heon, Lee, Changjin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598615/
https://ncbi.nlm.nih.gov/pubmed/32987772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102745
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