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A preparative chiral separation of hydroxychloroquine using supercritical fluid chromatography

A robust supercritical chromatography (SFC) method using an Enantiocel C2–5 column was developed for the multigram separation of the enantiomers of hydroxychloroquine (HCQ), affirming its use as a scalable technology and ability to provide quantities of each enantiomer for clinical evaluation. The e...

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Detalhes bibliográficos
Publicado no:J Chromatogr A
Main Authors: Wilson, Laura J., Mi, Charles, Kraml, Christina M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598365/
https://ncbi.nlm.nih.gov/pubmed/33166894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2020.461661
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