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Critical Impact of Different Conserved Endoplasmic Retention Motifs and Dopamine Receptor Interacting Proteins (DRIPs) on Intracellular Localization and Trafficking of the D(2) Dopamine Receptor (D(2)-R) Isoforms

The type 2 dopamine receptor D(2) (D(2)-R), member of the G protein-coupled receptor (GPCR) superfamily, exists in two isoforms, short (D(2S)-R) and long (D(2L)-R). They differ by an additional 29 amino acids (AA) in the third cytoplasmic loop (ICL3) of the D(2L)-R. These isoforms differ in their in...

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Publicat a:Biomolecules
Autors principals: Blagotinšek Cokan, Kaja, Mavri, Maša, Rutland, Catrin Sian, Glišić, Sanja, Senćanski, Milan, Vrecl, Milka, Kubale, Valentina
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598153/
https://ncbi.nlm.nih.gov/pubmed/32977535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10101355
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