Carregant...

Low frequency TP53 hotspot mutation contributes to chemoresistance through clonal expansion in acute myeloid leukemia

TP53 mutations (TP53mut) in AML patients associate with poor prognosis that may affect therapy and outcome. In addition to TP53 mut patients, TCGA AML patient sequencing data shows that there are around 3% of patients have detectable low frequency TP53mut reads. Importantly, these patients showed wo...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Leukemia
Autors principals: Yan, Bowen, Chen, Qinwei, Xu, Jianfeng, Li, Wei, Xu, Bing, Qiu, Yi
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7597970/
https://ncbi.nlm.nih.gov/pubmed/31988438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0710-7
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!