EBV-EBNA1 constructs an immunosuppressive microenvironment for nasopharyngeal carcinoma by promoting the chemoattraction of Treg cells

BACKGROUND: Nasopharyngeal carcinoma (NPC) is primarily caused by the Epstein-Barr virus (EBV) infection in NPC endemic areas. EBNA1 is an EBV-encoded nuclear antigen, which plays a critical role in the maintenance and replication of EBV genome. However, the mechanisms of EBNA1-promoted NPC immune e...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Huo, Shaofen, Luo, Yunfan, Deng, Rui, Liu, Xiong, Wang, Jie, Wang, Lu, Zhang, Bao, Wang, Fan, Lu, Juan, Li, Xiangping
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7597532/
https://ncbi.nlm.nih.gov/pubmed/33122398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001588
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