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Human macrophages engineered to secrete a bispecific T cell engager support antigen-dependent T cell responses to glioblastoma
BACKGROUND: Targeted and effective treatment options are needed for solid tumors, including glioblastoma (GBM), where survival rates with standard treatments are typically less than 2 years from diagnosis. Solid tumors pose many barriers to immunotherapies, including therapy half-life and persistenc...
Gardado en:
| Publicado en: | J Immunother Cancer |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMJ Publishing Group
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7597484/ https://ncbi.nlm.nih.gov/pubmed/33122397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001202 |
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