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Radiation induces an inflammatory response that results in STAT3-dependent changes in cellular plasticity and radioresistance of breast cancer stem-like cells

PURPOSE: Pro-inflammatory cytokines within the tumor microenvironment, such as IL-6, contribute to the maintenance of stem cells and promote their survival following treatment. The IL-6/STAT3 pathway is a key regulator of genes involved in cancer progression. Activation of STAT3 promotes expansion o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Radiat Biol
Egile Nagusiak: Arnold, Kimberly M., Opdenaker, Lynn M., Flynn, Nicole J., Appeah, Daniel Kwesi, Sims-Mourtada, Jennifer
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596771/
https://ncbi.nlm.nih.gov/pubmed/31850822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553002.2020.1705423
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