Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer

Ischemia reperfusion injury (IRI) during liver-metastasis resection for treatment of colon cancer may increase the risk of further metastasis. Peroxisome proliferator-activated receptor-γ (PPARγ) activation has been observed to exert a protective effect against IRI and IRI-induced metastasis of hepa...

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Publicat a:Sci Rep
Autors principals: Tashiro, Yoshihiko, Nishino, Hiroto, Higuchi, Takashi, Sugisawa, Norihiko, Fukuda, Yasunari, Yamamoto, Jun, Inubushi, Sachiko, Aoki, Takeshi, Murakami, Masahiko, Singh, Shree Ram, Bouvet, Michael, Hoffman, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596558/
https://ncbi.nlm.nih.gov/pubmed/33122687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75210-6
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