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Cerebrospinal Fluid IgM Levels in Association With Inflammatory Pathways in Multiple Sclerosis Patients

BACKGROUND: Intrathecal immunoglobulin M (IgM) synthesis has been demonstrated in the early disease stages of multiple sclerosis (MS) as a predictor factor of a worsening disease course. Similarly, increased cerebrospinal fluid (CSF) molecules related to B-cell intrathecal activity have been associa...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Magliozzi, Roberta, Mazziotti, Valentina, Montibeller, Luigi, Pisani, Anna I., Marastoni, Damiano, Tamanti, Agnese, Rossi, Stefania, Crescenzo, Francesco, Calabrese, Massimiliano
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596330/
https://ncbi.nlm.nih.gov/pubmed/33192314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.569827
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