Carbonic Anhydrase 12 Protects Endplate Cartilage From Degeneration Regulated by IGF-1/PI3K/CREB Signaling Pathway

Lumbar intervertebral disc degeneration (IVDD) is the most common cause of low back pain (LBP). Among all the factors leading to IVDD, lumbar cartilage endplate (LCE) degeneration is considered a key factor. In the present study, we investigate the effect and regulation of carbonic anhydrase 12 (CA1...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Zhao, Xing, Shen, Panyang, Li, Haidong, Yang, Yute, Guo, Jiandong, Chen, Shuai, Ma, Yan, Sheng, Jiamin, Shen, Shuying, Liu, Gang, Fang, Xiangqian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596245/
https://ncbi.nlm.nih.gov/pubmed/33178705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.595969
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