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Lactate Exposure Promotes Immunosuppressive Phenotypes in Innate Immune Cells

INTRODUCTION: Lactate secreted by tumors is not just a byproduct, but rather an active modulator of immune cells. There are few studies aimed at investigating the true effect of lactate, which is normally confounded by pH. Such a knowledge gap needs to be addressed. Herein, we studied the immunomodu...

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Publicado en:Cell Mol Bioeng
Autores principales: Sangsuwan, Rapeepat, Thuamsang, Bhasirie, Pacifici, Noah, Allen, Riley, Han, Hyunsoo, Miakicheva, Svetlana, Lewis, Jamal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596145/
https://ncbi.nlm.nih.gov/pubmed/33184582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-020-00652-x
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