IAP inhibitor, Embelin increases VCAM-1 levels on the endothelium, producing lymphocytic infiltration and antitumor immunity

There is an increasing unmet need for successful immunotherapeutic interventions. Lymphocyte extravasation via tumor tissue endothelial cells (TECs) is required for lymphocyte infiltration into tumor sites. This study aimed to investigate the clinical significance of dysfunctional TECs in pancreatic...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Nakajima, Kosei, Ino, Yoshinori, Yamazaki-Itoh, Rie, Naito, Chie, Shimasaki, Mari, Takahashi, Mami, Esaki, Minoru, Nara, Satoshi, Kishi, Yoji, Shimada, Kazuaki, Hiraoka, Nobuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595596/
https://ncbi.nlm.nih.gov/pubmed/33178497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1838812
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