Method feasibility for cross-species testing, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for non-human primate serum samples

An anti-Zaire Ebola virus (EBOV) glycoprotein (GP) immunoglobulin G (IgG) enzyme linked immunosorbent assay (ELISA) was developed to quantify the serum levels of anti-EBOV IgG in human and non-human primate (NHP) serum following vaccination and/or exposure to EBOV. This method was validated for test...

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Publicado en:PLoS One
Autores principales: Niemuth, Nancy A., Rudge, Thomas L., Sankovich, Karen A., Anderson, Michael S., Skomrock, Nicholas D., Badorrek, Christopher S., Sabourin, Carol L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595334/
https://ncbi.nlm.nih.gov/pubmed/33119638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241016
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