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Clinical implications of the log linear association between LDL-C lowering and cardiovascular risk reduction: Greatest benefits when LDL-C >100 mg/dl

BACKGROUND: The log linear association between on-treatment LDL-C levels and ASCVD events is amplified in higher risk patient subgroups of statin versus placebo trials. OBJECTIVES: Update previous systematic review to evaluate how the log linear association influences the magnitude of cardiovascular...

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Pubblicato in:PLoS One
Autori principali: Robinson, Jennifer G., Jayanna, Manju Bengaluru, Bairey Merz, C. Noel, Stone, Neil J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595281/
https://ncbi.nlm.nih.gov/pubmed/33119602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240166
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