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Genome editing of CCR5 by CRISPR-Cas9 in Mauritian cynomolgus macaque embryos
The discovery that CCR5 serves as an R5-HIV-1 co-receptor, coupled with findings of protection from HIV infection in individuals lacking CCR5, led to the exploration of novel therapeutic strategies for HIV infection based on genome editing of CCR5. Advancing translation of CCR5-mutant-based cellular...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7595107/ https://ncbi.nlm.nih.gov/pubmed/33116147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75295-z |
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