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Genome editing of CCR5 by CRISPR-Cas9 in Mauritian cynomolgus macaque embryos
The discovery that CCR5 serves as an R5-HIV-1 co-receptor, coupled with findings of protection from HIV infection in individuals lacking CCR5, led to the exploration of novel therapeutic strategies for HIV infection based on genome editing of CCR5. Advancing translation of CCR5-mutant-based cellular...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7595107/ https://ncbi.nlm.nih.gov/pubmed/33116147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75295-z |
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