Patient-derived SARS-CoV-2 mutations impact viral replication dynamics and infectivity in vitro and with clinical implications in vivo

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally with more than 33 million patients diagnosed, taking more than a million lives. Abundant mutations were observed but the functional consequences of these mutations are largely unknown. We report the mutation spectru...

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Publicat a:Cell Discov
Autors principals: Yao, Hangping, Lu, Xiangyun, Chen, Qiong, Xu, Kaijin, Chen, Yu, Cheng, Minghui, Chen, Keda, Cheng, Linfang, Weng, Tianhao, Shi, Danrong, Liu, Fumin, Wu, Zhigang, Xie, Mingjie, Wu, Haibo, Jin, Changzhong, Zheng, Min, Wu, Nanping, Jiang, Chao, Li, Lanjuan
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595057/
https://ncbi.nlm.nih.gov/pubmed/33298872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-00226-1
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