Brown Adipose Expansion and Remission of Glycemic Dysfunction in Obese SM/J Mice

We leverage the SM/J mouse to understand glycemic control in obesity. High-fat-fed SM/J mice initially develop poor glucose homeostasis relative to controls. Strikingly, their glycemic dysfunction resolves by 30 weeks of age despite persistent obesity. The mice dramatically expand their brown adipos...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Carson, Caryn, Macias-Velasco, Juan F., Gunawardana, Subhadra, Miranda, Mario A., Oyama, Sakura, St. Pierre, Celine L., Schmidt, Heather, Wayhart, Jessica P., Lawson, Heather A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594587/
https://ncbi.nlm.nih.gov/pubmed/33027654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108237
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