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A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux

Macroautophagy (autophagy) targets cytoplasmic cargoes to the lysosome for degradation. Like all vesicle trafficking, autophagy relies on phosphoinositide identity, concentration, and localization to execute multiple steps in this catabolic process. Here, we screen for phosphoinositide phosphatases...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Allen, Elizabeth A., Amato, Clelia, Fortier, Tina M., Velentzas, Panagiotis, Wood, Will, Baehrecke, Eric H.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594499/
https://ncbi.nlm.nih.gov/pubmed/32915229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201909073
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