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Combinatorial multivalent interactions drive cooperative assembly of the COPII coat

Protein secretion is initiated at the endoplasmic reticulum by the COPII coat, which self-assembles to form vesicles. Here, we examine the mechanisms by which a cargo-bound inner coat layer recruits and is organized by an outer scaffolding layer to drive local assembly of a stable structure rigid en...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Stancheva, Viktoriya G., Li, Xiao-Han, Hutchings, Joshua, Gomez-Navarro, Natalia, Santhanam, Balaji, Babu, M. Madan, Zanetti, Giulia, Miller, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594496/
https://ncbi.nlm.nih.gov/pubmed/32997735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202007135
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