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Loss of CBX2 induces genome instability and senescence-associated chromosomal rearrangements
The polycomb group protein CBX2 is an important epigenetic reader involved in cell proliferation and differentiation. While CBX2 overexpression occurs in a wide range of human tumors, targeted deletion results in homeotic transformation, proliferative defects, and premature senescence. However, its...
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| Foilsithe in: | J Cell Biol |
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| Main Authors: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Rockefeller University Press
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7594495/ https://ncbi.nlm.nih.gov/pubmed/32870972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201910149 |
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