Inhibiting CDK6 Activity by Quercetin Is an Attractive Strategy for Cancer Therapy

[Image: see text] Cyclin-dependent kinase 6 (CDK6) is a potential drug target that plays an important role in the progression of different types of cancers. We performed in silico and in vitro screening of different natural compounds and found that quercetin has a high binding affinity for the CDK6...

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Veröffentlicht in:ACS Omega
Hauptverfasser: Yousuf, Mohd, Khan, Parvez, Shamsi, Anas, Shahbaaz, Mohd, Hasan, Gulam Mustafa, Haque, Qazi Mohd Rizwanul, Christoffels, Alan, Islam, Asimul, Hassan, Md. Imtaiyaz
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594119/
https://ncbi.nlm.nih.gov/pubmed/33134711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03975
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