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Computer-Aided Estimation of Biological Activity Profiles of Drug-Like Compounds Taking into Account Their Metabolism in Human Body

Most pharmaceutical substances interact with several or even many molecular targets in the organism, determining the complex profiles of their biological activity. Moreover, due to biotransformation in the human body, they form one or several metabolites with different biological activity profiles....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Filimonov, Dmitry A., Rudik, Anastassia V., Dmitriev, Alexander V., Poroikov, Vladimir V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593915/
https://ncbi.nlm.nih.gov/pubmed/33050610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207492
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